Advanced hepatocellular carcinoma (HCC) with pulmonary metastasis (PM) has a poor prognosis, and optimal treatment strategies remain controversial. This study compared pulmonary metastasectomy and combination immunotherapy with targeted molecular therapies for advanced HCC with pulmonary metastasis, indicating that pulmonary metastasectomy provided longer survival than immunotherapy combined with targeted molecular therapies and has the potential to become the optimal treatment for highly selected HCC patients with resectable PM.

The increasing prevalence of myopia is a global health concern, with high myopia increasing the risk of vision damage. This necessitates the use of artificial intelligence (AI) for early diagnosis, prevention, and management of myopia.  Now, a Pediatric Investigation review sheds light on potential applications of AI in the early identification, risk assessment, and prevention of myopia. It further highlights the challenges and current development status of AI technology in the field of myopia.

Understanding how genes influence complex behaviors remains one of biology’s most fascinating challenges. Now, however, in a recent study, researchers from Japan compiled a comprehensive dataset documenting the behaviors of over 30,000 fruit flies across 105 genetically distinct strains. This valuable resource captures individual and group behaviors under various conditions, providing unparalleled insights into the genetic foundations of behavior that could ultimately enable a better understanding of human health conditions and ecology.

The American Academy of Sleep Medicine has released a new position statement emphasizing the clinical significance of sleepiness and its impact on performance, health, mood, safety, and quality of life. The position states that sleepiness is a critical patient-reported outcome that is associated with an increased risk for adverse health effects and diminished quality of life. The statement urges health care professionals, policymakers, and researchers to prioritize the evaluation, management, and treatment of sleepiness to improve public health.