A novel bioactive glass incorporated in a toothpaste significantly reduced tooth sensitivity through prompt and lasting symptom relief, results from an ADA Forsyth Institute-administered clinical trial showed.

The first-in-human trial established the safety and efficacy of Sensi-IP, a bioactive glass technology developed by IR Scientific. ADA Forsyth researchers found statistically significant reductions in tooth sensitivity scores in the test group compared to a control group using a common sodium fluoride (NaF) toothpaste.

Researchers discovered an indication hidden in the brain that may help doctors identify children suffering from a rare genetic disease earlier.

Cancer research laboratory tests can now be done using micro-physiological systems mimicking the human physiology, allowing greater predictive accuracy for human patient responses, thanks to an international scientific team led by HonorHealth Research Institute and the University of Arizona.

Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside cancer cells, killing the cells via oxidative stress while leaving healthy tissues alone.

Researchers from the University of British Columbia and the Berlin Institute of Health have developed a topical gene‑editing approach that can correct disease‑causing mutations in human skin tissue maintained in the lab. The method uses lipid nanoparticles—tiny fat‑based carriers—to deliver gene‑editing tools into the upper layers of the skin after a brief laser treatment. In tests, the team was able to edit genes directly within human skin samples and also correct a common mutation linked to autosomal recessive congenital ichthyosis (ARCI) in patient‑derived cells. While still early‑stage, this platform could open the door to future treatments for a range of rare genetic skin conditions.

Salk Institute researchers analyzed immune cells from 110 people and found that genetic differences and life experiences (sickness, vaccination history, environment) impact immune cells differently. The findings help explain why people respond differently to the same infections and treatments, and the study provides a foundation for personalized medicine to prevent disease onset, bolster immune health, or treat infectious diseases, cancers, and other immune disorders.