Researchers at the Lewis Katz School of Medicine at Temple University have identified a new strategy that may help repair damaged heart tissue by reactivating an important developmental gene.

Atrial fibrillation (AF) is the most common type of irregular heartbeat, and over time, it can worsen and become a permanent condition, a severe disorder that’s the leading preventable cause of ischemic stroke, according to the NIH. Nicolae Moise, a research scientist in the Department of Biomedical Engineering at Ohio State University (OSU), is using NCSA and OSC high-performance computing resources to explore the long-term progression of AF, in the hopes that his research can help with treatments that can stop AF before it becomes a lifelong condition.

By understanding differences in how people’s brains are wired, clinicians may be able to predict who would benefit from a self-guided anxiety care app, according to a new analysis from a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The preliminary study suggested that young people with weaker connections between two brain areas involved in both attending to and regulating responses to anxiety were more likely to benefit from a self-guided anxiety care app than those with stronger connections.

About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To better understand why some tumors resist chemotherapy and identify better ways to treat those cancers, researchers at Baylor College of Medicine have conducted a detailed molecular analysis of MIBC tumors. The results offer potential new ways to identify which patients will benefit from chemotherapy and reveal possible new treatment strategies.

Despite national guidelines, state laws and known safety benefits of child passenger restraint systems (CRS), suboptimal practices were found in nearly 70% of children under 13 years old who were involved in car crashes with a fatality from 2011 to 2021, according to a study published in the journal Traffic Injury Prevention.