Global study maps how bacterial communities shape the health of lakes and reservoirs
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Dec-2025 19:11 ET (24-Dec-2025 00:11 GMT/UTC)
•Circular RNA (circRNA) cancer vaccines advance next-gen immunotherapy with enhanced stability and efficacy for precision oncology.
•CircRNAs encode tumor antigens and adjuvants, enabling personalized vaccines to modulate heterogeneity and gene expression.
•Novel delivery methods, like lipid nanoparticles and exosomes, improve circRNA vaccine efficacy.
•Combining circRNA vaccines with therapies like T-cell receptor-engineered T-cell therapy enhances anti-cancer efficacy.
New simulator and computational tool generate realistic “virtual tissues” and map cell-to-cell “conversations” from spatial transcriptomics data.
The tools could accelerate AI-driven discoveries in cancer, brain disorders and precision medicine by revealing which genes control how cells interact.
New smart surfaces, known as metasurfaces, can shape and utilize light to activate cells in the body, offering a gentle and wireless approach to treating health conditions. By manipulating light for medicine and biomedical devices, they enable treatments for vision, hearing, heart, and neurological disorders. Combined with virtual reality and advanced controls, these tools could help doctors design non-invasive and personalized treatments for a wide range of medical needs.
In a study published in Nature Communications, researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), together with international collaborators, examined whether methylene blue could mitigate brain injury during severe malaria, and whether a practical set of blood biomarkers could help clinicians identify cerebral malaria early and track how patients respond to treatment.