Bonn, July 25, 2025 – Despite unclear evidence and contrary to national and international guidelines, the practice of fundal pressure continues to be used in many maternity clinics. A new qualitative study conducted as part of the MAM-Care research project at the University Hospital Bonn (UKB) – in cooperation with the University of Bonn and the University Hospital Cologne – is the first to systematically investigate how women subjectively experience this controversial obstetric procedure.

The laminin-411 protein is vital for the formation of the myelin membrane by oligodendrocytes, report researchers from Japan. Furthermore, the A4G47 peptide from the E8 region of laminin-411 was found to be the main active amino acid sequence that drives myelin formation. The research findings have the potential to transform current cell culture practices to study myelination and may enable the development of novel therapeutic agents to treat demyelinating diseases.  

A research team led by Prof. HU Junjie from the Institute of Biophysics of the Chinese Academy of Sciences has uncovered a pivotal mechanism by which beta-coronaviruses assemble in cells, providing a novel target for developing broadly antiviral strategies.

Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition often overlooked due to the lack of diagnostic tools, may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and metabolism.