Scientists uncover critical role of membrane protein topology in beta-coronaviruses assembly
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Aug-2025 12:11 ET (14-Aug-2025 16:11 GMT/UTC)
A research team led by Prof. HU Junjie from the Institute of Biophysics of the Chinese Academy of Sciences has uncovered a pivotal mechanism by which beta-coronaviruses assemble in cells, providing a novel target for developing broadly antiviral strategies.
Researchers from the Hospital del Mar Research Institute and Yale University, in the United States, have demonstrated how the action of certain genes on precursor cells of brain formation can cause alterations linked to cortical malformations but also to the origin of neuropsychiatric diseases such as autism or bipolar disorder.
The study, published in Nature Communications, is the first of its kind. It has been able to simulate the function of a list of nearly 3,000 genes linked to these pathologies during human brain development.
The work opens a window to understand the origin of these diseases and to develop treatment opportunities through gene therapy.Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition often overlooked due to the lack of diagnostic tools, may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and metabolism.
A new study published by researchers from the University of Oxford, the Wildlife Conservation Society (WCS), CIFOR-ICRAF, and institutional partners reveals a disconnect between media and public perceptions on the risks of consuming wild meat in Central Africa during COVID-19 and sheds light on the complex relationship between media reporting, community beliefs, and behaviour change — offering important lessons for wildlife management and public health strategies.