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Medicine & Health

Updates every hour. Last Updated: 31-Oct-2026 01:15 ET (31-Oct-2026 05:15 GMT/UTC)

EP4 receptor offers new possibilities for more precise treatment of inflammatory diseases

Compuscript Ltd
Peer-Reviewed Publication

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases. By examining the diverse actions of the PGE2–EP4 signaling pathway, the article demonstrates how targeting this receptor could provide more precise approaches to controlling inflammation.

Journal: Genes & Diseases

Targeting mitochondria could open new routes to personalized treatment for triple-negative breast cancer

Compuscript Ltd
Peer-Reviewed Publication

A deeper understanding of mitochondrial function could create new opportunities for treating triple-negative breast cancer (TNBC), one of the most aggressive and difficult-to-treat forms of breast cancer. The complex relationship between mitochondrial dynamics, energy metabolism and cancer-cell survival is revealing potential targets that could support more personalized treatment strategies.

Journal: Genes & Diseases

DNA vaccines emerge as a versatile platform for the future of immunization

Compuscript Ltd
Peer-Reviewed Publication

A new review published in Genes & Diseases highlights the expanding potential of DNA-based vaccines as a flexible platform for preventing infectious diseases, treating cancer and strengthening preparedness for future disease outbreaks. The article charts the evolution of DNA vaccination from early concepts in the 1990s to increasingly sophisticated technologies with applications across infectious disease, oncology and precision medicine.

Journal: Genes & Diseases

Johns Hopkins Medicine researchers identify promising biological marker linked to treatment-resistant psychosis

Johns Hopkins Medicine
Peer-Reviewed Publication

In a preliminary study using blood and spinal fluid samples from 200 people, Johns Hopkins Medicine researchers say they have evidence that a well-studied blood pressure regulation protein appears to also be a marker for and perhaps play a role in treatment-resistant schizophrenia and other psychoses.

Journal: JAMA Psychiatry
Funder: Brain & Behavior Research Foundation

Dr. Botond Roska, a collaborator of Semmelweis University, receives vision research’s top award

Semmelweis University
Grant and Award Announcement

Dr. Botond Roska, a former student and visiting professor at Semmelweis University, has received the António Champalimaud Vision Award for his achievements in developing optogenetic therapy to restore vision. He shared the award, one of the world’s most prestigious honors in vision research, with French American ophthalmologist and researcher José-Alain Sahel. The world-renowned researcher, who lives in Switzerland, has collaborated with Semmelweis University for 15 years and believes this joint work has contributed to his achievements. In an interview with our website, he also discussed the current state of research into treating certain forms of blindness, when a therapy that partially restores vision could become more widely available, and the results of a five-year research project conducted jointly with the university that has just concluded.

Up to $51.7 million ARPA-H award backs Georgetown University and Buck Institute co-led “super team” to predict and intervene in harmful protein changes before disease begins

Georgetown University
Grant and Award Announcement

A research “super team” co-led by the Buck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments. The four-year effort is expected to lead to new ways of detecting, slowing and treating neurodegenerative diseases and cancer, with an initial focus on Alzheimer's disease and Ewing sarcoma.

Funder: Advanced Research Projects Agency for Health

Psilocybin providers follow safety guidelines, study finds

Washington University in St. Louis
Peer-Reviewed Publication

WashU researchers found that Oregon’s licensed psilocybin centers consistently followed recommended safety practices for screening clients, though steep operating and licensing costs strain both the centers and people seeking care.

Journal: Health Affairs Scholar

Healthy diet during pregnancy associated with reduced risk of infant colic, eczema

Harvard T.H. Chan School of Public Health
Peer-Reviewed Publication

Infants born to mothers who ate a healthy, Mediterranean-style diet during pregnancy were at lower risk for colic and eczema, according to a new study by researchers at Harvard T.H. Chan School of Public Health, Boston Children’s Hospital, and Harvard Pilgrim Health Care Institute. The researchers also found that regularly consuming seafood during pregnancy helped lower an infant’s risk for these conditions.

Journal: JAMA Network Open

When it comes to health care access, more isn't always better

University of California - San Francisco
Peer-Reviewed Publication

Hospitals and policymakers routinely face a difficult question when investing in specialized emergency services: Will adding another facility improve care, or would those resources do more good somewhere else? New UC San Francisco research suggests the answer depends heavily on what people already have access to. In nearly 600,000 California heart attack patients, survival rates improved after specialized services opened in communities that previously lacked timely access. But where those services were already available, opening another facility increased the likelihood of receiving procedures only slightly and did not improve survival rates.

Journal: JAMA Network Open

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