Being incarcerated and living in areas where more have gone to jail is associated with higher death rates
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Nov-2025 19:11 ET (14-Nov-2025 00:11 GMT/UTC)
Mount Sinai study emphasizes the need for health care interventions during and after incarceration and within associated communities
Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-TIGET, Milan) have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system. The study, published in Cell Reports Medicine, outlines new strategies to overcome this hurdle, improving both the safety and efficacy of gene-editing-based therapies for inherited blood disorders.