This review examines inflammation as a physiological defense mechanism against infectious agents, physical trauma, reactive oxygen species (ROS), and metabolic stress, which, under dysregulated conditions, may progress into chronic diseases. Nanomedicine, which integrates nanotechnology with medicine, suppresses inflammatory signaling pathways and overexpressed pro-inflammatory cytokines, such as ROS, to address inflammation-related pathologies. Current advances in nanomaterial design and synthesis strategies are systematically analyzed, with parallel discussions on toxicity mechanisms, influencing factors, and evaluation methods that are critical for clinical translation. Applications of functional nanomaterials are highlighted in the context of refractory inflammatory conditions, including wound healing, gastrointestinal disorders, and immune, neurological, or circulatory diseases, along with targeted delivery strategies. Persistent challenges in nanomedicine development, such as biocompatibility optimization, precise biodistribution control, and standardized toxicity assessment, are critically assessed. By bridging material innovation with therapeutic efficacy, this review establishes a framework for advancing nanomedicine to improve treatment outcomes while addressing translational barriers.

Since the Corona era, people's interest in health management has increased significantly compared to before. In addition, the emergence of multidrug-resistant bacteria through antibiotics has begun to have a great impact on human health. Therefore, the research team would like to report the synergy effect of antibacterial activity using wearable organic light-emitting diodes and natural antibacterial substances against staphylococcus aureus. This is research on a platform that is more convenient than past treatment methods and can suppress the development of multidrug-resistant staphylococcus aureus.

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Nano, how proteins in cells can be controllably activated through heating, an effect that can be used to initiate programmed cell death.

A peer-reviewed journal focusing on immunity and inflammation field is now available on Springer Nature platform. “We are proud to announce the launch of Immunity & Inflammation, an innovative and high-profile platform dedicated to cutting-edge research,” share Professor Xuetao Cao and Professor Jules Hoffmann, Co-Editors-In-Chief of the journal. The journal will focus on critical insights across the spectrum of immunology and invites researchers around the world to join in exploring breakthroughs in immunity and inflammation.