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Updates every hour. Last Updated: 5-Oct-2025 10:11 ET (5-Oct-2025 14:11 GMT/UTC)
Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer’s disease.
Colorectal cancer is one of the most common and deadly cancers worldwide, and treatment decisions for older patients remain highly debated. Now, researchers have found that oxaliplatin-based chemotherapy significantly improves survival only in stage III colorectal cancer patients aged 70 or younger. For patients over 70, the drug offered no survival advantage and led to higher rates of treatment discontinuation due to toxicity. Importantly, stage II patients showed no survival benefit at any age.
This study deciphers the characteristics of human spinal cord neural stem cells (hscNSCs) specific to cervical, thoracic, and lumbar segments, and establishes an efficient method for amplifying hscNSCs from different spinal segments. A key finding: when transplanted into rat models with thoracic spinal cord injury (SCI), thoracic hscNSCs show superior therapeutic effects compared to cervical or lumbar hscNSCs. The research clarifies the critical role of segment-specific hscNSCs in spinal cord injury repair, offering valuable insights for targeted SCI treatment strategies.
Alzheimer’s disease is the leading cause of dementia, yet its underlying mechanisms remain unclear. A new review published in the Chinese Medical Journal highlights how immune cells, including T and B cells, contribute to brain inflammation in Alzheimer’s. By pulling together findings from recent decades, the study suggests that targeting these immune responses could open the door to better treatments and diagnosis, offering hope against one of the most devastating neurological disorders worldwide.