Researchers build bone marrow model entirely from human cells
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Nov-2025 21:11 ET (19-Nov-2025 02:11 GMT/UTC)
Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this cellular complexity in the laboratory using only human cells. The novel system could reduce the need for animal experiments for many applications.
A research paper by scientists at the Capital Medical University evaluated sex differences in stroke recurrence among patients with symptomatic intracranial atherosclerotic stenosis (sICAS) and assess the efficacy of remote ischemic conditioning (RIC) in the RICA (chronic remote ischemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis) trial.
The new research paper, published on Jun. 6 in the journal Cyborg and Bionic Systems, evaluated 3,033 sICAS patients across 84 Chinese stroke centers, with a median follow-up of 3.5 years. The findings highlight the need to consider sex in clinical decision-making for RIC administration.