This study evaluates virtual 3D scanned prosections in gross anatomy education. Twenty-nine medical students were divided into physical or virtual teaching groups. Both groups showed significant post-test score improvements, with no significant difference between them. While students found 3D scans effective for learning and exam preparation, they preferred dissection for lab experience. Results indicate virtual 3D scans are a valuable supplementary tool but not a replacement for traditional dissection in medical education. 

Teacher emotion recognition (TER) is crucial for classroom dynamics, yet limited by scarce multimodal data and feature modeling. We present a multimodal TER dataset with 102 lessons and 2,170 video segments, annotated with interaction-based emotional tags. We propose an Emotion Dual-Space Network (EDSN) with a Commonality Space (ECSC) using central moment differences to align modalities, and a Discrimination Space (EDSC) using gradient reversal and orthogonal projection to extract unique features. EDSN achieves 77.0% accuracy and 0.769 F1-score on the dataset, outperforming state-of-the-art models, demonstrating its effectiveness in educational emotion recognition. 

This study determined cryo-EM structures of midnolin-proteasome complexes, providing mechanistic insights to midnolin-catalyzed substrate degradation. Based on structural and mechanistic understanding, authors have engineered the midnolin system for targeted degradation of desired substrates, and provide the first proof-of-principle for degrading a non-native therapeutically high-profile target that is otherwise undruggable.

The reticular architecture of metal-organic frameworks (MOFs) enables not only systematic but also creative tuning of their functionalities. A recent study involving forty structurally related MOFs demonstrated how to precisely integrate and regulate two types of electrochromic cores within the MOF architectures through mild linker modifications and straightforward crystal engineering. The underlying logic is reminiscent of a conventional color palette—yet elevated to molecular-level precision, offering promising prospects for future electronic applications.

Flavanols are plant-derived compounds with an astringent taste, exhibiting pro- or antioxidant properties depending on the environment. Due to poor bioavailability, their health-promoting mechanism remains unclear. A new study identified their action via the brain-gut axis.  A single oral intake of flavanols stimulated brain regions involved in memory and sleep-wake regulation, and increased sympathetic nervous activity, a stress response. These findings may lead to future applications, such as the development of next-generation foods.