Tissue engineering the pancreas: Working with three-dimensional pancreatic models (organoids), derived from mouse cells, researchers combined computer simulations with experiments to find out what controls the shape of lumens (fluid-filled cavities) during the development of the pancreas.

Proliferation, Pressure, Permeability: The shape of the lumen depends on the balance between the cell proliferation rate and the pressure in the lumen. Low pressure and high proliferation produce more complex or ‘star-shaped’ lumens. The pressure in lumens remain low because the surrounding pancreatic tissue is permeable.

Implications for organ development and disease: The discovered mechanisms can be potentially relevant to other organs with complex ductal systems and to common cystic diseases. Furthermore, these findings could be used to develop new therapeutic strategies, including testing the effects of drugs for diseases.

Solid oxide fuel cells (SOFCs) offer a clean alternative to fossil fuel-based power generation, but their high operating temperatures hinder widespread use. In a recent study, researchers from Japan developed ultra-thin, highly ordered samarium-doped cerium oxide electrolyte films that overcome the long-standing issue of grain boundary resistance, enabling efficient operation at much lower temperatures. Their design achieved record-setting oxide-ion conductivity and paves the way for safer, more affordable SOFCs for sustainable power generation.

A new study has identified the first known gene in eggplant that provides resistance to begomoviruses, a group of plant viruses responsible for major crop losses worldwide. The research shows that virus-resistant plants accumulate far less viral DNA than susceptible plants, linked to a gene encoding an exonuclease involved in viral defense. This previously unknown resistance pathway could support the breeding of virus-resistant crops, strengthen food security, and reduce reliance on chemical pesticides.

The hunting of large whales goes back much further in time than previously thought. New research from the Institute of Environmental Science and Technology at the Universitat Autònoma de Barcelona (ICTA-UAB) and the Department of Prehistory of the UAB reveals that Indigenous communities in southern Brazil were hunting large cetaceans 5,000 years ago, around a thousand years before the earliest documented evidence from Arctic and North Pacific societies.

The COSTA system pioneers cascade spatio-temporal attention plus memory-distilled iterative cross-modal alignment, cutting redundant video clutter and lifting dialogue response quality to new SOTA on long, dynamic videos.

SGR turns adversarial shortcuts into teachers, isolating invariant subgraph rationales and delivering the first XGL framework provably robust against spurious correlations on both synthetic and real-world graphs.