Glioma is an aggressive and malignant brain tumor with a poor prognosis, accounting for nearly half of all primary malignant brain tumors. Current treatments have limited efficacy and are often accompanied by side effects. Furthermore, the genetic diversity within glioma complicates the development of targeted therapies, warranting more research on the topic.

Metabolic dysfunction-associated steatotic liver disease (MASLD), a multifactorial disease that encompasses a spectrum of pathological conditions, ranging from simple steatosis, metabolic dysfunction-associated steatohepatitis (MASH), and fibrosis/cirrhosis, is associated with increased mortality. However, there are currently no standard diagnostic markers or effective treatments. Hence, there is an urgent need to elucidate the pathogenesis of MASLD to identify viable therapeutic targets.

Promoting the acceptance of clinical studies about traditional Chinese medicine (TCM) interventions by the international community is a key strategy for internationalization of TCM. However, the complexities of TCM interventions – in terms of its theories, practice patterns, and components – pose significant challenges in designing and implementing clinical studies that are well accepted by the international community. This article summarized the current status of clinical studies about TCM interventions published in international journals, explored underlying barriers to promoting their global acceptance, and discussed potential strategies for future development.

In the paper published on Science of Traditional Chinese Medicine(STCM), the authors utilized synthetic biology technology to create the first artificial herbal cell (AHC) based on a traditional Chinese medicine (TCM) formulation: Compound Danshen Yeast 1.0. This breakthrough provides foundational technology for producing TCM formulations through one-step fermentation using simple carbon sources like glucose and ethanol—eliminating the need for wild harvesting or cultivation of medicinal herbs. By harnessing synthetic biology, the team reprogrammed a single yeast strain to simultaneously synthesize three classes of active ingredients—notoginsenosides (protopanaxadiol), tanshinone diterpenoid (miltiradiene), and borneol.

There are 157 non-native species have successfully invaded Dongting Lake, which is the second largest freshwater lake in China. Although some non-native species become important species in local aquaculture, aquarium trade and other industries. Many non-native species have caused significantly negative impacts on native biodiversity, environmental safety, human health and sustainable development.