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Updates every hour. Last Updated: 13-Jan-2026 09:11 ET (13-Jan-2026 14:11 GMT/UTC)
Design of de-tumbling device for improving the de-tumbling performance of uncooperative space target
Beijing Institute of Technology Press Co., LtdFighting highway subgrade settlement on the roof of the world
Tsinghua University PressPermafrost degradation on the Qinghai-Tibet Plateau is accelerating under climate warming, causing roadbed settlement, waterlogging, thawing interlayers, and long-term instability in high-altitude highways. The study reviews global and Chinese permafrost engineering practices, identifies the mechanisms behind pervasive subgrade deformation, and highlights challenges in current “permafrost-protection” design approaches. It proposes a third design principle — proactively improving foundation conditions — advancing from passive protection to active treatment. The work further summarizes shallow and deep foundation treatment techniques, evaluates engineering applications, and outlines development trends such as improved hydrological investigation, long-term monitoring, and novel construction materials.
- Journal
- Journal of Highway and Transportation Research and Development (English Edition)
A DIY, fly-powered fix for food scraps
University of California - Riverside- Journal
- Waste Management
Medical breakthrough could help immune system target cancer cells
University of SharjahScientists present a new approach that could empower the immune system to combat cancer cells and pave the way for new treatments for this deadly disease. The new insight stems from an extensive review of research on TIGIT, a protein known to inhibit the immune system’s ability to effectively attack cancer cells. Currently, a single drug can successfully neutralize TIGIT and enable immune cells to combat cancer in laboratory settings; however, clinical trials have been less successful.
- Journal
- Cell Death and Disease
- Funder
- Xi’an-Jiaotong Liverpool University has provided the financial support for the Article Publishing Charge (APC) of this article.
Adapting grapevines for the future: Insights from wild grape species
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
Dual engineering of catalyst and sacrificial agent for efficient photo-biocatalytic CO2 reduction
Higher Education PressAn efficient and highly selective NADH regeneration system has been constructed by integrating M with CIS microspheres via facile electrostatic self-assembly with L-AA as a sacrificial agent.
- Journal
- Acta Physico-Chimica Sinica
3D printing revolutionizes mass spectrometry
Shanghai Jiao Tong University Journal CenterMass spectrometry (MS) is an analytical technique for molecular identification and characterization, with applications spanning various scientific disciplines. Despite its significance, MS faces challenges in widespread adoption due to cost constraints, instrument portability issues, and complex sample handling requirements. In recent years, 3D printing has emerged as a technology across industries due to its cost-effectiveness, customization capabilities, and rapid prototyping features. This review explores the integration of 3D printing with MS technology to overcome existing limitations and enhance biomedical analysis capabilities. We first categorize mainstream 3D printing methods and assess their potential in MS applications. We also discuss their roles in different MS categories such as liquid chromatography mass spectrometry (LCMS), gas chromatography mass spectrometry (GCMS), ambient ionization mass spectrometry (AIMS), and matrix-assisted laser desorption/ionization MS (MALDI MS) in biomedical research. Additionally, we highlight the current challenges and future research directions for advancing 3D printing-assisted mass spectrometry, emphasizing its role in enabling portable, cost-effective, and customized MS solutions for biomedical analysis.
- Journal
- LabMed Discovery
Transforming tumor diagnostics with CRISPR/Cas
Shanghai Jiao Tong University Journal CenterPrecise tumor diagnosis and treatment require the support of abundant molecular information. However, conventional molecular diagnostic technologies gradually fail to satisfy the demands of clinical therapy due to limited detection performance. Benefiting from highly specific target sequence recognition and efficient cis/trans cleavage activity, CRISPR/Cas system has been widely employed to construct novel molecular diagnostic strategies, hailed as the “next-generation molecular diagnostic technology”. This review focuses on recent advances in CRISPR molecular diagnostic systems for the detection of tumor variant gene, protein, and liquid biopsy biomarker, and outlines strategies for CRISPR in situ molecular detection. In addition, we explore general principles and development trends in the construction of CRISPR molecular diagnostic system and emphasize the revolutionary impact that it has brought to the field of molecular diagnostics.
- Journal
- LabMed Discovery
Physics of 2D materials for developing smart devices
Shanghai Jiao Tong University Journal CenterRapid industrialization advancements have grabbed worldwide attention to integrate a very large number of electronic components into a smaller space for performing multifunctional operations. To fulfill the growing computing demand state-of-the-art materials are required for substituting traditional silicon and metal oxide semiconductors frameworks. Two-dimensional (2D) materials have shown their tremendous potential surpassing the limitations of conventional materials for developing smart devices. Despite their ground-breaking progress over the last two decades, systematic studies providing in-depth insights into the exciting physics of 2D materials are still lacking. Therefore, in this review, we discuss the importance of 2D materials in bridging the gap between conventional and advanced technologies due to their distinct statistical and quantum physics. Moreover, the inherent properties of these materials could easily be tailored to meet the specific requirements of smart devices. Hence, we discuss the physics of various 2D materials enabling them to fabricate smart devices. We also shed light on promising opportunities in developing smart devices and identified the formidable challenges that need to be addressed.
- Journal
- Nano-Micro Letters