Article Highlights
Updates every hour. Last Updated: 2-May-2025 18:09 ET (2-May-2025 22:09 GMT/UTC)
21-Jan-2025
Breakthrough in Sustainable Biomaterials: Innovations in Polyacrylic Acid Hydrogels
Journal of Bioresources and Bioproducts
A new study explores the integration of biopolymers with polyacrylic acid hydrogels, highlighting their potential applications in bioresources and bioproducts. This research offers insights into the development of sustainable and functional biomaterials for various fields, including flexible electronics and biosensing.
- Journal
- Journal of Bioresources and Bioproducts
20-Jan-2025
miR-618 rs2682818 C>A polymorphism decreases neuroblastoma risk in tumors originating from the adrenal gland
Xia & He Publishing Inc.
MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene expression by either degrading or inhibiting the translation of mRNAs and have significant roles in the development of various tumors. A polymorphism (rs2682818) in miR-618 has been confirmed to be correlated with susceptibility to various cancers. Nonetheless, its role has not been investigated in neuroblastoma to date. Therefore, we assessed whether the miR-618 rs2682818 C>A polymorphism was correlated with neuroblastoma risk in the Chinese population.
- Journal
- Cancer Screening and Prevention
20-Jan-2025
Molecular markers and survival outcomes in patients with metastatic colorectal cancer at the Hospital de Especialidades Eugenio Espejo
Xia & He Publishing Inc.
Colorectal cancer (CRC) ranks third in incidence and second in mortality worldwide. In Ecuador, there are 2,481 new CRC cases per year and 2,366 cancer deaths yearly. CRC presents in stages III-IV in more than 50% of patients. The standard treatment for CRC is chemotherapy, with an overall survival (OS) of 29–31 months. The status of biomarkers KRAS, NRAS, BRAF, and MSI provides prognostic and predictive value. This study aimed to determine OS and progression-free survival (PFS) for metastatic CRC based on these molecular markers with a minimum follow-up of one year.
- Journal
- Cancer Screening and Prevention
20-Jan-2025
Stray DNA fragments challenge CRISPR precision
King Abdullah University of Science & Technology (KAUST)Simple fixes of unintended large genetic insertions uncovered in genome editing offer improved safety and reliability.
- Journal
- Communications Biology
20-Jan-2025
Free radical scavenging activity of cymbopogon citratus (stapf) and evaluation of its antiproliferative effect on MG-63 human osteosarcoma cells
Xia & He Publishing Inc.
In the etiology of a large number of metabolic disorders, free radicals are involved in the first line, in particular in the physiopathology of cancers. This interventional study aimed to evaluate in vitro the DPPH radical scavenging activity of a hydroalcoholic extract of Cymbopogon citratus (HAECC) and its antiproliferative activity in human osteosarcoma.
- Journal
- Cancer Screening and Prevention
20-Jan-2025
Fluorescent guidance: A leap in bladder cancer surgery
Maximum Academic Press
Researchers have introduced an innovative surgical technique for treating bladder cancer that could revolutionize the field of urological oncology.
- Journal
- UroPrecision
20-Jan-2025
3D printed surgical guides for cardiovascular surgeries
Vrije Universiteit Brussel
Ida Anna Cappello of the Heart Rhythm Management Centre of the University Hospital Brussels (VUB) has made significant strides in the field of biomedical engineering by developing innovative 3D printed surgical guides for cardiovascular procedures. Her research, conducted in close collaboration with cardiologists and cardiac surgeons, holds the potential to revolutionize surgical accuracy in complex heart surgeries.
- Journal
- Journal of Clinical Medicine
17-Jan-2025
A simple model for an intricate, ever-evolving structure
Chan Zuckerberg BiohubNew research, published recently in Proceedings of the National Academy of Sciences, uncovers the unique dynamics governing the endoplasmic reticulum (ER)’s evolution and addresses the long-standing mystery of just how this organelle sustains life at the cellular level, with implications for understanding disease.
- Journal
- Proceedings of the National Academy of Sciences
17-Jan-2025
“Louvers” on the SPARC fusion device should exhaust gases as hot as a star
DOE/US Department of Energy
New studies have found that using louvers at the bottom of a fusion device creates local conditions that can reduce the temperature of the edge plasma, ensuring the plasma is not hot enough to damage the device. Specifically, the louvers allow the hot plasma to “detach” from the walls of the device, spreading out the heat. The work, on the SPARC machine, aids in progress toward fusion energy production.
- Journal
- Nuclear Fusion