The findings, published recently in Cell Reports Medicine, offer new clues to why some viral infections appear to trigger autoimmune disease.

Impaired neuromusculoskeletal function due to conditions such as stroke, osteoarthritis, cerebral palsy, Parkinson’s disease, limb amputation, spinal cord injury, traumatic brain injury and cancer is a leading cause of disability and affects roughly 1.7 billion people worldwide, including 19% of the U.S. adult population. Researchers led by Rice University’s Benjamin J. Fregly have developed a treatment design software that implements a novel personalized medicine approach for addressing this important societal problem.

Miriam Merad, MD, PhD, an internationally acclaimed immunologist and oncologist, has been awarded the title of Chevalier de la Légion d'honneur [Knight of the Legion of Honor] by the French Republic. The prestigious distinction, presented at the Consulate General of France in New York by the Ambassador of France to the United States, honors Dr. Merad’s groundbreaking contributions to macrophage biology and immunology and her leadership in transforming the landscape of translational research and precision medicine. One of France’s highest civilian honors, the Legion of Honor recognizes individuals who have made extraordinary contributions to their fields and society at large. Dr. Merad was selected for her visionary research elucidating the role of innate immune cells in cancer and chronic inflammatory disease, as well as her commitment to fostering global scientific collaboration and advancing human health.

Grassroots rugby concussion guidelines need to be improved as players’ brains remain altered despite them being symptom free and cleared to play, researchers have found. The University of Essex is the first to follow an amateur club across a gruelling 22-game season using brain imaging technology. The study led by Dr Ben Jones found seven out of eight concussed players still had abnormal brain responses 25 days after injury - despite feeling well enough to return to the field under Rugby Football Union clearance protocols.

This review explores the complex interplay between the microbiome and human aging, highlighting how dysbiosis impacts host physiology and health, particularly in relation to genomic stability and telomere attrition. Recent advances in cellular and molecular biology have underscored the role of both intrinsic and extrinsic factors in human aging, with the microbiome emerging as a key determinant of host physiology and health. Dysbiosis—disruptions in microbiome composition—is linked to various age-related diseases and impacts genomic stability and telomere attrition, the progressive shortening of telomeres that limits cell division and contributes to aging. This review examines how microbiome dynamics influence aging by triggering inflammation, oxidative stress, immune dysregulation, and metabolic dysfunction, all of which affect two primary hallmarks of aging: genomic instability and telomere attrition. Understanding these interactions is essential for developing targeted interventions to restore microbiome balance and promote healthy aging, offering potential treatments to extend healthspan and alleviate aging-related diseases. The convergence of microbiome and aging research promises transformative insights and new avenues for improving global population well-being.