CLEVELAND, Ohio (Oct 21, 2025)—Many women during menopause complain about brain fog, which includes symptoms like forgetfulness, trouble concentrating, and mental fatigue, often due to fluctuating hormone levels. A literature review was conducted to examine published studies that explore the link between structural brain changes during menopause and cognitive, emotional and physiological outcomes. Findings from this review will be presented at the 2025 Annual Meeting of The Menopause Society in Orlando October 21-25.