The stomach’s ‘second brain’ is more in sync with the mind during mental distress
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Updates every hour. Last Updated: 7-Oct-2025 21:11 ET (8-Oct-2025 01:11 GMT/UTC)
Bentham Science has announced the release of its newest title Organoid Technology: Disease Modelling, Drug Discovery, and Personalized Medicine, a pioneering study that captures the transformative role of organoid systems in advancing human health research.
Researchers have created what could be called “skin in a syringe”. The gel containing live cells can be 3D printed into a skin transplant, as shown in a study conducted on mice. This technology may lead to new ways to treat burns and severe wounds. The study was led from the Center for Disaster Medicine and Traumatology and Linköping University in Sweden, and has been published in Advanced Healthcare Materials.
Bentham Science announces the release of an essential reference for researchers, educators, and industry professionals engaged in drug discovery and experimental pharmacology. Zebrafish Models for Experimental Pharmacology: A Handbook presents a clear, practical, and methodologically rich approach to harnessing the Zebrafish as a powerful model organism in biomedical research.
Gastric cancer that metastasizes to the peritoneum, or the lining of the abdominal cavity, has a very poor prognosis and is challenging to treat. Now, a group of researchers has developed mRNA-based vaccines that can target tumor-specific ‘neoantigens.’ In combination with anti-PD1 therapy, these vaccines show high antitumor efficacy against gastric cancer with peritoneal metastasis. This approach can potentially be expanded in order to develop ‘personalized’ cancer vaccines for complicated cancer cases.
Inhibiting a specific gene, MET, in combination with standard chemotherapy and immunotherapy, enhances treatment efficacy and limits tumor growth in small cell lung cancer (SCLC). The study, led by the Hospital del Mar Research Institute, analyzed the effect of MET inhibition in mouse models and studied gene expression in patient tumor samples. The results are published in Cell Reports Medicine. Researchers aim to pursue this line of research with a clinical trial involving patients.
A new systematic review of 172 studies including data from over 12 million adolescents across 166 countries reveals that while cross-national adolescent mental health research including low- and middle-income countries has expanded significantly, large gaps remain in global representation.